![]() ![]() The substance of a lymph node is divided into the outer cortex and the inner medulla. Įach lymph node is surrounded by a fibrous capsule, which extends inside a lymph node to form trabeculae. Lymph nodes are kidney or oval shaped and range in size from 2 mm to 25 mm on their long axis, with an average of 15 mm. When inflamed or enlarged, lymph nodes can be firm or tender.Ĭross-section of a lymph node with sections labelled.1) Capsule 2) Subcapsular sinus 3) Germinal centre 4) Lymphoid nodule 5) Trabeculae Lymphadenopathy refers to glands that are enlarged or swollen. ![]() ![]() The condition of lymph nodes is very important in cancer staging, which decides the treatment to be used and determines the prognosis. Lymph nodes become inflamed or enlarged in various diseases, which may range from trivial throat infections to life-threatening cancers. A lymph node is enclosed in a fibrous capsule and is made up of an outer cortex and an inner medulla. In the lymphatic system a lymph node is a secondary lymphoid organ. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles including cancer cells, but have no detoxification function. They are major sites of lymphocytes that include B and T cells. ![]() A large number of lymph nodes are linked throughout the body by the lymphatic vessels. A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. ![]()
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